Sample services provided to companies
Archive 2025-2026

DIAGNICS

Case Studies

These sample analysis results are drawn from the comprehensive reports we deliver to medical device and heart valve companies. Each example has been adapted from client‑ready documentation, with all proprietary information removed.

We Quantify!

Hemodynamics & 3D fluid dynamics
Hydrodynamic performance
Durability / fatigue
Structural integrity
Thrombogenicity & hemolysis

Our analysis is not just descriptive;
it is quantitative and comprehensive!

Diagnics leverages a cutting-edge, integrated approach that combines several technologies for comprehensive & multiphase assessments of
intraventricular and valvular flow and structural dynamics.

Imaging
modalities

echocardiography
tomographic particle image velocimetry

Computational Algorithms

fully patient-specific modelling
extensively validated models

fully patient-specific Tests

in vitro bench test
ex vivo bench test

DIAGNICS Delivers FDA‑Expected Computational Models for Advanced Heart Valve Assessment

Rigorous computational evidence for next‑generation heart valve innovation

Structural mechanics

leaflet stress/strain
frame deformation
fatigue hot spots
crimping/expansion
interaction with calcified anatomy

Hemodynamics

velocity fields
shear stress
regions of stasis/recirculation
thrombogenic risk
regurgitant jets

Fluid–structure interaction (FSI)

coupled behavior
leaflet motion under pulsatile flow
dynamic coaptation

Virtual trials

Device performance across anatomical variations

New surgical mitral valve

Client sample Patient 1
Hydrodynamic in vitro test
Echo-based vortex analysis

SESAME

Client sample Patient 2
Intraventricular momentum thrust directional distribution
Pre and four-month post procedure comparison

Transcatheter mitral valve

Client sample Patient 3
Streamlines
Post procedure regurgitation

Transcatheter mitral valve

Client sample Patient 4
Mitral and intraventricular streamlines and velocity magnitude
Three-month & one-year followup

Transcatheter mitral valve

Client sample Patient 5
4D Flow MRI
Post procedure analysis

Transcatheter mitral valve

Client sample Animal 1
Animal study
Time-averaged wall shear stress

Transcatheter mitral valve

Client sample Animal 2
Animal study
Velocity field and streamlines

New transcatheter aortic valve

Client sample Patient 6
Doppler-based P-V loop analysis
Pre and post intervention comparison

Transcatheter mitral valve

Client sample Animal 3
Animal study
Streamlines

Transcatheter mitral valve

Client sample Animal 4
Animal study
Velocity field

Transcatheter mitral valve

Client sample Animal 5
Animal study
Intraventricular momentum thrust directional distribution

Transcatheter mitral valve

Client sample Animal 6
Animal study
Post procedure regurgitation

Transcatheter mitral valve

Client sample Patient 7
P-V loop and intraventricular flow analyses
Pre and post procedure comparison

Transcatheter mitral valve

Client sample Patient 8
P-V loop and intraventricular flow analyses
Pre and post procedure comparison

SESAME

Client sample Patient 9
Intraventricular flow analyses
Pre and four-month post procedure comparison

Transcatheter mitral valve

Client sample Patient 10
Streamlines
Post procedure regurgitation

Mitral valve intervention

Client sample Patient 11
Velocity
Pre and post intervention comparison

Transcatheter mitral valve

Client sample Patient 12
Streamlines and velocity
Pre and post intervention comparison

Transcatheter mitral valve

Client sample Patient 13
Intraventricular momentum thrust directional distribution
Three-month & one-year followup

New surgical mitral valve

Client sample Patient 14
Streamlines
Comparison of a new surgical mitral valve with existing valves.

Obstructive cardiomyopathy

Client sample Patient 15
Hemodynamics performance
Doppler echocardiography based computational investigation

Transcatheter mitral valve

Client sample Animal 7
Animal study
Q Criterion

New surgical mitral valve

Client sample Patient 16
Hydrodynamic in vitro test
Doppler echocardiography measurements

New surgical mitral valve

Client sample Patient 17
Hydrodynamic in vitro test
Pressure and flow waveforms

New surgical mitral valve

Client sample Patient 18
Hydrodynamic in vitro test
Closure volume

Transcatheter mitral valve

Client sample Patient 19
Intraventricular blood stagnation
Pre and three-month post intervention comparison