Empowering
Cardiovascular Innovation
Through Computational Excellence

Diagnics Inc. delivers non-invasive, patient-specific computational biomechanics to transform cardiovascular diagnostics, prognostics, and intervention planning.

Where Science and Engineering Drive Clinical Impact

Leveraging proprietary technologies, Diagnics Inc. delivers noninvasive, rapid, and cost-effective heart analysis and quantification through advanced, patient-specific computational modeling.

Diagnics’ computational expertise & technology:

Provides diagnostic & prognostic insights

Supports preclinical studies

Supports clinical studies

Facilitates FDA clearance

Serves

Device Manufacturers

Clinicians

Researchers

Unlike AI-based approximations, our mechanistic, patient-specific models ensure unmatched reliability, precision, and interpretability—tailored to each patient’s unique physiology.

Diagnics’ approach enables comprehensive, high-fidelity evaluations supporting every stage of therapy advancement and cardiovascular device development from concept to clinical application.

Trusted insights
Tailored evaluations
Transformative outcomes

Why Diagnics’ Computational service?

Current diagnostic methods have restrictive limitations that hinder cardiac device innovations.

Diagnics’ computational technology bridges the gaps current clinical diagnostic methods.

❌ Clinical Diagnostic methods

✅ Diagnics’ Computational Solution

Cardiac Catheterization
Invasive, risky, and impractical for routine use.

Non-Invasive Modeling
Safe, repeatable, and patient-specific.

MRI
Poor temporal resolution, high cost, and not suitable for patients with implants.

High-Fidelity Simulations
Fast, cost-effective, and universally applicable.

Doppler Echocardiography
Lacks 3D hemodynamic and biomechanical detail.

3D Biomechanical Insight
Detailed, quantitative, and clinically actionable.

Furthermore …

Diagnics will generate extensive reports filled with thorough interpretations, providing deep insights and detailed analysis. These reports are integral in understanding complex cardiovascular conditions and informing clinical decisions.

Transformative Structural Heart Analyses

Our computational expertise enables innovators and clinical teams to noninvasively, swiftly, and cost-effectively analyze and quantify heart structures (valves and ventricles) and associated devices (e.g., transcatheter heart valves) with the following three core computational analyses:

Doppler-Based Ventricular Pressure-Volume (P-V) Loop Analysis

Our technology enables non-invasive P-V loop analysis using noninvasive Doppler echocardiography data.

P-V loop analysis can be used to quantify the impact of cardiac diseases, interventions, surgeries, or medications on cardiac function, hemodynamics, and left ventricle remodeling.

Analysis of Heart Valve Dynamics

This analysis quantifies the three-dimensional distribution of strain, stress, and leaflet-specific material properties in heart valves.

Mechanical stresses are a primary contributor to the failure of both native and prosthetic valves, serving as strong prognostic indicators of valvular disease progression and implant durability.

Patient-Specific Blood Flow Analysis

This analysis supports clinical teams, medical device innovators, and manufacturers in conducting detailed investigations of patient-specific blood flow dynamics.

By leveraging advanced computational modeling and simulation techniques, it enables precise evaluation of hemodynamic performance.

Vortex and micro – vortex analysis
(aortic valve)

These insights play a pivotal role in guiding the design, refinement, and rigorous validation of cardiovascular devices, directly contributing to their safety, effectiveness, and reliability in real-world clinical settings.

Intraventricular flow and vortex analysis post-TMVR

Intraventricular vortex analysis with prosthetic vs native mitral valves

Example in slow filling phase

Bileaflet mechanical mitral valve

Effective orifice area (cm2): 4.8

Mean pressure gradient (mmHg): 2.1

Vortex formation time: 6.4

Sphrecity index: 1.5

Trileaflet mitral bioprosthesis valve

Effective orifice area (cm2): 3.3

Mean pressure gradient (mmHg): 2.4

Vortex formation time: 12.2

Sphrecity index: 1.2

Native mitral valve

Effective orifice area (cm2): 5.1

Mean pressure gradient (mmHg): 0.5

Vortex formation time: 3.5

Sphrecity index: 2.0